Patent Image
A METHOD OF PRODUCING NATURE IDENTICAL CARTILAGE TISSUE VIA GENE DELIVERY
Reference Number
025418/0070
Application Number
2017/14838
Technologies
Health Technologies
Technology Readiness Level (TRL)
Readiness Level 2
Patent Number
2017/14838
Application Status
Application Phase
Keywords
cartilage tissue defects tissue regeneration.
Relevant Sectors
Health
Patent Protection

2017/14838 Application Phase_Turkey  PCT/TR2018/050536 Country Stage_WIPO  18870535.4 Application Phase_EPO

Summary

The present invention relates to method of cultivating rat mesenchymal stem cells to which tissue transglutaminase gene (variant 2) is transferred by lentiviral transduction, on three dimensional poly (1, 4-butylene succinate ) / poly (L-lactic acid) tissue scaffolds. The objective of the present invention is to cultivate the cells to which gene delivery is performed using lentivirus, on polymeric tissue scaffolds, and then to use them in cartilage tissue defects and tissue regeneration.